WHAT WE DO
Bioimaging, at its essence, measures life-systems onto two-dimensional (2D) sensors. However natural signals –with three-dimensions for space, one for time, one for electromagnetic spectrum, etc.– are multi-dimensional (nD). How do you design and build optical systems with 2D sensors to acquire these nD signals? Traditional answer is to simply measure only the dimensions we think are informative.
In Wadduwage lab, we take a different approach. Using data and modern machine-learning tools, we “learn” an informative 2D representation of the nD signal constrained to the physics of light. To do this, we need: (0) data; (1) machine learning algorithms that understands the physics of light; (2) processes to fabricate the unconventional optics designed by the algorithms; (3) physical instruments with the fabricated optics; and finally (4) computational algorithms to extract information from the measurements.
So, along with our collaborators we:
(0) Collect large datasets of living-systems,
(1) Build a new breed of wave-physics-informed neural network models and optimizers,
(2) Design and fabricate customized (or “learned”) optics,
(3) Build new optical systems with “learned” optics, and
(4) Utilize state-of-the-art neural networks from computer vision to extract data from the optical systems.
Zheng, C., Park, J.K., Yildirim, M., Boivin, J.R., Xue, Y., Sur, M., So, P.T. and Wadduwage, D.N., 2021. De-scattering with Excitation Patterning enables rapid wide-field imaging through scattering media. Science Advances, 7(28), p.eaay5496.
Wadduwage, D.N., Singh, V.R., Choi, H., Yaqoob, Z., Heemskerk, H., Matsudaira, P. and So, P.T., 2017. Near-common-path interferometer for imaging Fourier-transform spectroscopy in wide-field microscopy. Optica, 4(5), pp.546-556.
Herath, K., Haputhanthri, U., Hettiarachchi, R., Kariyawasam, H., Ahmad, A., Ahluwalia, B.S., Edussooriya, C.U. and Wadduwage, D., 2022. Differentiable Microscopy Designs an All Optical Quantitative Phase Microscope. arXiv preprint arXiv:2203.14944.
Raja Naeem AHMAD
High School Intern
Undergraduate Student, University of Waterloo
Congratulations to Udith, Jathurshan and Mithunjha for their paper acceptance at ICASSP.
Congratulations to Jathurshan, Udith, Mithunjha and their team for achieving,
second runners-up at IEEE Video and Image Processing (VIP) Cup!
Congratulations to Mithunjha and Jathurshan on their paper acceptance to EMBC.
Congratulations to Kithmini, Ramith & their team for